Tuesday, November 28, 2006

Drug used on wounded GIs could be fatal

American military doctors in Iraq have injected more than 1,000 of the war's wounded troops with a potent and largely experimental blood-coagulating drug despite mounting medical evidence linking it to deadly blood clots that lodge in the lungs, heart and brain.

The drug, called Recombinant Activated Factor VII, is approved in the U.S. for treating only rare forms of hemophilia affecting about 2,700 Americans. In a warning last December, the Food and Drug Administration said that giving it to patients with normal blood could cause strokes and heart attacks. Its researchers published a study in January blaming 43 deaths on clots that developed after injections of Factor VII.

The U.S. Army Medical Command considers Factor VII to be a medical breakthrough in the war, giving frontline physicians a powerful new means of controlling bleeding that can be treated otherwise only with surgery and transfusions. It has posted guidelines at military field hospitals encouraging its liberal use in all casualties with severe bleeding, and doctors in Iraq routinely inject it into patients upon the mere anticipation of deadly bleeding to come.

FULL STORY

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